Skin Wellness
Skin Renewal
Using ultra-fine needles to create controlled micro-channels in the skin, microneedling signals your body to rebuild from within. Collagen and elastin surge to the surface, revealing skin that looks and feels noticeably tighter, smoother, and more refreshed. At Biolite Wellness, we don't stop there. By pairing microneedling with advanced topicals like Rejuran, we give your skin the tools it needs to heal faster and deliver results that go beyond what microneedling alone can achieve.
Microneedling is a nonsurgical, minimally invasive treatment that addresses a broad range of skin concerns, fine lines, and wrinkles, acne scars, uneven tone and texture, and overall dullness. The procedure is well-tolerated with little to no downtime. Mild redness and swelling may occur for a few days following treatment. With a series of sessions spaced several weeks apart, patients experience meaningful, lasting improvements in skin clarity and texture.
The micro-channels created during treatment also enhance the absorption of topical therapies applied immediately after. This is what makes microneedling uniquely powerful, it primes the skin to receive advanced serums and biologics at a level far deeper than topical application alone can achieve. At Biolite, we customize every session with the right enhancement for your skin goals.
Microneedling works in three natural phases, each building on the last to deliver lasting skin transformation.
Fine needles gently penetrate the skin's surface, signaling the body to begin its natural repair process. Collagen and elastin production ramp up in response, laying the foundation for firmer, smoother skin.
The open channels allow topical treatments to absorb deeply into the dermis — far beyond what standard application allows. We can customize each session with Rejuran (PDRN).
Over the following weeks, new collagen remodels beneath the surface. Skin gradually becomes clearer, smoother, and more youthful — with results that continue to improve across a series of sessions.
Microneedling is powerful on its own, but pairing it with the right topical therapy takes your results to the next level. We offer evidence-based enhancements tailored to your skin goals.
Microneedling creates thousands of micro-channels in the skin and topical Rejuran takes full advantage of that. Rejuran is a polynucleotide based treatment clinically recognized for repairing and regenerating skin at a cellular level. When applied during your session, it absorbs deeply to stimulate collagen production, restore skin structure, and accelerate healing in a way surface-level products simply can't match.
The result is smoother texture, reduced pore appearance, improved firmness, and a lasting glow. It's especially powerful for those targeting acne scarring, fine lines, or skin laxity.If you're investing in microneedling, adding topical Rejuran is one of the best upgrades you can make to amplify your results.
Every treatment plan is overseen by our physician-led team, ensuring a clinical standard of care that goes beyond the typical med spa experience.
A topical numbing cream is applied prior to every session, making treatment comfortable and well-tolerated for even the most sensitive skin types.
Conveniently located to serve Irvine, Tustin, Newport Beach, and the greater Orange County area.
Not sure if microneedling is right for you? Start with a complimentary consultation to personalize your treatment plan.
Before treatment, a topical anesthetic is applied to ensure your comfort throughout the procedure.
During treatment, fine needles create micro-channels across the treatment area. Your chosen enhancement serum is applied immediately after to maximize absorption and results.
After treatment, you may notice mild redness, swelling, warmth, or slight flaking for up to one week. These are normal healing responses and resolve on their own. Most patients feel comfortable returning to daily activities right away.
Microneedling may not be appropriate for those with active skin infections, bleeding disorders, uncontrolled diabetes, eczema, psoriasis, rosacea, keloid scarring, current isotretinoin use, pregnancy, or recent facial surgery within the past six months. A full evaluation during your complimentary consultation will confirm whether the treatment is right for you.
The procedure is well-tolerated. A topical numbing cream is applied before treatment, ensuring comfort throughout. Most patients describe the sensation as a light vibration. If PRX-T33 is added, a brief, mild stinging may occur but resolves within minutes.
Most patients see optimal results with a series of 3–6 sessions spaced 4–6 weeks apart. The number varies depending on your skin concerns and goals. Your provider will create a personalized plan during your complimentary consultation at Biolite Wellness.
Downtime is minimal. Mild redness, swelling, warmth, and light flaking are common and typically resolve within one week. Most patients return to daily activities immediately. Adding exosomes or PRP/PRF can significantly shorten the visible recovery period.
Visible improvements can appear in as little as two weeks, with results continuing to develop over several months as new collagen forms. Longevity depends on your skin's natural aging process and how consistently you maintain your results with follow-up treatments.
Microneedling may not be appropriate for those with active skin infections, bleeding or clotting disorders, uncontrolled diabetes, eczema, psoriasis, rosacea, keloid scarring, current isotretinoin use, pregnancy, or recent facial surgery within the past six months. A full evaluation at your consultation will confirm whether this treatment is right for you.
Rejuran — also known as polynucleotides (PDRN or PN) — is a skin biorevitalization treatment derived from salmon DNA. It works by delivering biological building blocks directly into the skin to stimulate cellular repair, enhance hydration, and rebuild collagen and elastin. It is widely used across Europe and Asia and is increasingly recognized as one of the most effective skin-healing therapies available.
Microneedling creates thousands of micro-channels in the skin, allowing Rejuran polynucleotides to penetrate deep into the dermis — far beyond what topical application can achieve. This combination amplifies the regenerative effects of both treatments, accelerating collagen production, improving skin texture, and reducing the appearance of scars and fine lines more effectively than either treatment alone.
Yes. Rejuran is biocompatible and well-tolerated. The polynucleotides used are highly purified and have an excellent safety profile. Side effects are typically mild and limited to temporary redness or swelling at the treatment site. As with all treatments at Biolite Wellness, your provider will review your health history to confirm it is appropriate for you.
Rejuran is ideal for patients looking to improve overall skin quality, reduce fine lines, restore hydration, minimize acne scars, and achieve a healthier, more luminous complexion. It is particularly well-suited for those with sensitive or compromised skin that needs deep repair and regeneration rather than just surface-level treatment.
Many patients notice improved skin hydration and radiance within 2–4 weeks of their first session. Collagen remodeling and deeper structural improvements continue to develop over 1–3 months. For best results, a series of 2–4 sessions is recommended, tailored to your individual skin goals.